Lionel Messi will miss El Clasico after being ruled out for three weeks with a fractured arm as Barcelona beat Sevilla 4-2 to go top of La Liga.
The Argentine was left writhing in agony after landing heavily on his right arm after colliding with Franco Vazquez.
He was still in obvious discomfort as he left the field in the 26th minute.
Just moments earlier the Barcelona captain had scored a sublime goal to put Barcelona 2-0 up.
Messi had also set up Philippe Coutinho for the opener on two minutes.